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Targeting cell cycle has become the gold standard for metastatic breast cancer (MBC), being cyclin-dependent kinase inhibitors (CDKIs) cornerstones of its treatment, alongside radiotherapy (RT).To date, no definite evidence regarding snack size milk duds safety and efficacy of the combination of CDKIs plus radiotherapy (RT) is currently available.P
Abstract It has been reported that neuregulin1 (NRG1) improves glucose tolerance in healthy and diabetic rodents.In vitro studies also suggest that NRG1 regulates myocyte oxidative capacity.To confirm this observation in vivo, we evaluated the effect on mitochondrial function of an 8-week le emt multitool 2.0 treatment with NRG1 in db/db diabetic m